{"id":42517,"date":"2022-02-02T17:51:10","date_gmt":"2022-02-02T20:51:10","guid":{"rendered":"https:\/\/condor.fabbricaweb.com.br\/?p=42517"},"modified":"2026-08-24T12:11:28","modified_gmt":"2026-08-24T15:11:28","slug":"terapia-de-luz-e-ritmos-biologicos","status":"publish","type":"post","link":"https:\/\/condor.fabbricaweb.com.br\/en\/terapia-de-luz-e-ritmos-biologicos\/","title":{"rendered":"Light therapy and biological rhythms"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">The organism of living beings is governed by circadian oscillations. In humans, these oscillations are controlled by the suprachiasmatic nucleus (SCN) located in the hypothalamus. Thus, the NSQ regulates the expression of genes in all the peripheral clocks, directing the control of all the body&#8217;s functions, such as the production of immune system cells, hormone secretion and the regulation of the sleep-wake cycle. For more information, read https:\/\/condor.fabbricaweb.com.br\/o-que-ritmo-circadiano\/.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The sleep-wake cycle is regulated by various synchronizers such as physical exercise, social work and study routines, food and light. Melanopsins, photoreceptor cells located in the retina, capture light and transmit this information to the NSQ via the hypothalamic retinal tract. Light is therefore the most powerful information for regulating circadian rhythms<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Humans have adapted to light and the body understands that daytime is the time to be awake and nighttime, when there is no light, is the time to rest. This regulation is complex and depends on the activation of various genes and hormones. Thus, when the sleep-wake cycle is misaligned with the light-dark cycle, mood disorders, cardiometabolic diseases such as diabetes and hypertension, obesity, cardiovascular diseases, immunological diseases and reduced quality of sleep occur and, therefore, it is essential that synchrony is achieved (<a href=\"#_ENREF_1\">FISHBEIN; KNUTSON; ZEE, 2021<\/a>). However, some individuals suffer from rhythm disturbances, which significantly interfere with their personal, social and occupational lives. These disorders can be treated through behavioral interventions (exposure to light, regulating exercise and eating schedules) and pharmacological ones (melatonin and melatonin agonists such as ramelteon and tasimelteon). For this article, the focus will be on behavioral treatment and, specifically, light therapy.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Interestingly, the light stimulus shows different responses in the circadian timing system depending on the time of its application (<a href=\"#_ENREF_2\">GOOLEY, 2008<\/a>). For example, when applied in the morning, it causes a phase advance in the endogenous rhythms, which makes sleep occur earlier. On the other hand, when applied during the beginning of the biological night, it causes a phase delay, making the onset of sleep later<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"sindrome-da-fase-atrasada-de-sono\"><em><strong>Delayed sleep phase syndrome<\/strong><\/em><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">In delayed sleep phase syndrome, patients have late sleep onset times, at times that are incompatible with what is required by society (starting sleep between 2am and 6am). As a result, these patients find it difficult to get up and carry out activities at conventional times. In addition, there is usually sleep restriction and, consequently, daytime sleepiness which impairs day-to-day performance. The treatment consists of applying light early in the morning, as soon as you wake up. This will advance the sleep phase. Likewise, it is important to avoid light stimuli during the early evening (<a href=\"#_ENREF_4\">ROSENTHAL; JOSEPH-VANDERPOOL; LEVENDOSKY; JOHNSTON<em> et al.<\/em>, 1990<\/a>)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"sindrome-da-fase-avancada-de-sono\"><em><strong>Advanced sleep phase syndrome<\/strong><\/em><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">This disorder is characterized by a significant advance in sleep periods. Thus, these patients start sleeping between 6pm and 8pm, and wake up between 1am and 3am. For this reason, they feel sleepy in the late afternoon. Treatment consists of applying light at the beginning of the biological night, as well as avoiding exposure to light stimuli at the beginning of the night. Not only that, the patient should avoid exposure to light during the early hours of the morning to avoid undesirable phase advances.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"livre-curso\"><em><strong>Free course<\/strong><\/em><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Free running occurs when the individual is out of sync with the light-dark cycle and the perceived effect is a delay in the sleep phase each day (usually 5 to 15 minutes a day). This disorder is present almost exclusively in visually impaired individuals with optic nerve damage (<a href=\"#_ENREF_6\">SACK; LEWY; BLOOD; KEITH<em> et al.<\/em>, 1992<\/a>) and is rare in individuals with normal visual ability, usually being attributed to dysfunction of the light synchronization pathway due to tumors in the central nervous system, reduced sensitivity of the circadian system to light or inefficient exposure to light. In free-standing studies in patients with a normal visual system, light exposure was performed immediately upon waking up with the aim of synchronizing the sleep-wake cycle, and the objective was successfully achieved (<a href=\"#_ENREF_3\">HOBAN; SACK; LEWY; MILLER<em> et al.<\/em>, 1989<\/a>).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"irregularidade-do-ciclo-vigilia-sono\"><em><strong>Irregularity of the sleep-wake cycle<\/strong><\/em><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">In patients with this disorder, the sleep-wake cycle occurs in a disorganized way in the 24-hour cycle, with frequent napping, insomnia and excessive daytime sleepiness. Thus, the sleep-wake cycle cannot be completely defined in these patients (<a href=\"#_ENREF_2\">GOOLEY, 2008<\/a>). Generally, this disorder stems from neurological problems (dementia, brain damage or mentally handicapped individuals) or inadequate exposure to circadian synchronizers (light, physical exercise, food, social commitments). In addition, it can also occur in elderly or dementia patients living in institutions (e.g. nursing homes) due to constant light conditions and unregulated social schedules.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The main aim of treatment is to consolidate sleep at night and wakefulness during the day. Therefore, exposure to light during the day should be increased, as well as avoiding light at night. In addition, physical exercise and socialization should be encouraged during the light cycle of the day (<a href=\"#_ENREF_8\">ZEE; VITIELLO, 2009<\/a>).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"jet-lag\"><em><strong>Jet lag<\/strong><\/em><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">This transient disorder occurs after transmeridional journeys that cross more than 3 time zones. The symptoms result from the desynchronization between the internal timing system and the time at the destination. It usually takes 1 day for each zone crossed to adapt to the new destination. Symptoms include gastrointestinal disorders, excessive daytime sleepiness, insomnia, difficulty waking up in the morning, reduced cognitive performance and mood swings (<a href=\"#_ENREF_7\">SAMUELS, 2012<\/a>).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Light can be used to speed up adaptation and reduce the symptoms of <em>jet lag.<\/em> To do this, you need to consider the direction of travel and the adaptation you want to achieve (phase delay or phase advance). In general, when traveling east, you want a phase advance, so you need to apply the light stimulus as soon as you wake up. On the other hand, when traveling west, what is desired is a phase delay, so the application of the light stimulus is recommended at night (<a href=\"#_ENREF_5\">SACK; AUCKLEY; AUGER; CARSKADON<em> et al.<\/em>, 2007<\/a>).<\/p>\n\n\n\n<figure class=\"wp-block-image alignleft size-large is-resized\"><img fetchpriority=\"high\" decoding=\"async\" src=\"https:\/\/condor.fabbricaweb.com.br\/wp-content\/uploads\/2022\/02\/Actigrafo-luz-1024x1024.png\" alt=\"\" class=\"wp-image-42519\" width=\"403\" height=\"403\" srcset=\"https:\/\/condor.fabbricaweb.com.br\/wp-content\/uploads\/2022\/02\/Actigrafo-luz-1024x1024.png 1024w, https:\/\/condor.fabbricaweb.com.br\/wp-content\/uploads\/2022\/02\/Actigrafo-luz-300x300.png 300w, https:\/\/condor.fabbricaweb.com.br\/wp-content\/uploads\/2022\/02\/Actigrafo-luz-768x768.png 768w, https:\/\/condor.fabbricaweb.com.br\/wp-content\/uploads\/2022\/02\/Actigrafo-luz.png 1080w\" sizes=\"(max-width: 403px) 100vw, 403px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"como-avaliar-transtornos-de-ritmo\"><em><strong>How to assess rhythm disorders<\/strong><\/em><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">To assess and analyze rhythms, actigraphy can be used, which is the gold standard technique for evaluating biological rhythms. The actigraph is a device similar to a wristwatch and contains activity, light and temperature sensors. CONDOR&#8217;s software includes automatic calculations to analyze specific circadian rhythm variables, such as non-parametric analyses (L5, M10, IV and IS), spectrograms, periodograms and cosinors. It is also possible to analyze sleep-related variables such as total sleep time, sleep onset latency, sleep efficiency and awakenings after sleep onset. With this technique, it is possible to analyze the patient over long periods, making it ideal for checking whether the intervention adopted to treat the observed disorder is generating the expected results.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><a href=\"https:\/\/condor.fabbricaweb.com.br\/contato\/\" target=\"_blank\" rel=\"noreferrer noopener\"><img decoding=\"async\" width=\"1024\" height=\"427\" src=\"https:\/\/condor.fabbricaweb.com.br\/wp-content\/uploads\/2021\/08\/CONDOR-FOOTER-1-1024x427-1.png\" alt=\"\" class=\"wp-image-34124\" srcset=\"https:\/\/condor.fabbricaweb.com.br\/wp-content\/uploads\/2021\/08\/CONDOR-FOOTER-1-1024x427-1.png 1024w, https:\/\/condor.fabbricaweb.com.br\/wp-content\/uploads\/2021\/08\/CONDOR-FOOTER-1-1024x427-1-300x125.png 300w, https:\/\/condor.fabbricaweb.com.br\/wp-content\/uploads\/2021\/08\/CONDOR-FOOTER-1-1024x427-1-768x320.png 768w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><figcaption class=\"wp-element-caption\">https:\/\/condor.fabbricaweb.com.br\/<\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-3e41869c wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/condor.fabbricaweb.com.br\/contato\/\" target=\"_blank\" rel=\"noreferrer noopener\">Contact us<\/a><\/div>\n<\/div>\n    \t","protected":false},"excerpt":{"rendered":"<p>The organism of living beings is governed by circadian oscillations. In humans, these oscillations are controlled by the suprachiasmatic nucleus (SCN) located in the hypothalamus. Thus, the NSQ regulates the expression of genes in all the peripheral clocks, directing the control of all the body&#8217;s functions, such as the production of immune system cells, hormone [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":42518,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[11,10,12],"tags":[],"class_list":["post-42517","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-actigraphy","category-circadian-rhythm-and-health","category-sleep-and-health"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Light therapy and biological rhythms - Condor Instruments<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Light therapy and biological rhythms - Condor Instruments\" \/>\n<meta property=\"og:description\" content=\"The organism of living beings is governed by circadian oscillations. In humans, these oscillations are controlled by the suprachiasmatic nucleus (SCN) located in the hypothalamus. Thus, the NSQ regulates the expression of genes in all the peripheral clocks, directing the control of all the body&#8217;s functions, such as the production of immune system cells, hormone [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/condor.fabbricaweb.com.br\/en\/terapia-de-luz-e-ritmos-biologicos\/\" \/>\n<meta property=\"og:site_name\" content=\"Condor Instruments\" \/>\n<meta property=\"article:published_time\" content=\"2022-02-02T20:51:10+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-08-24T15:11:28+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/condor.fabbricaweb.com.br\/wp-content\/uploads\/2022\/02\/720x600-pt.png\" \/>\n\t<meta property=\"og:image:width\" content=\"720\" \/>\n\t<meta property=\"og:image:height\" content=\"600\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Condor\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Condor\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"7 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/condor.fabbricaweb.com.br\\\/en\\\/terapia-de-luz-e-ritmos-biologicos\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/condor.fabbricaweb.com.br\\\/en\\\/terapia-de-luz-e-ritmos-biologicos\\\/\"},\"author\":{\"name\":\"Condor\",\"@id\":\"https:\\\/\\\/condor.fabbricaweb.com.br\\\/#\\\/schema\\\/person\\\/86cd767bdd3b9c879fa81c8ceecb2aab\"},\"headline\":\"Light therapy and biological rhythms\",\"datePublished\":\"2022-02-02T20:51:10+00:00\",\"dateModified\":\"2026-08-24T15:11:28+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/condor.fabbricaweb.com.br\\\/en\\\/terapia-de-luz-e-ritmos-biologicos\\\/\"},\"wordCount\":1100,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/condor.fabbricaweb.com.br\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/condor.fabbricaweb.com.br\\\/en\\\/terapia-de-luz-e-ritmos-biologicos\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/condor.fabbricaweb.com.br\\\/wp-content\\\/uploads\\\/2022\\\/02\\\/720x600-pt.png\",\"articleSection\":[\"Actigraphy\",\"Circadian Rhythm and Health\",\"Sleep and Health\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/condor.fabbricaweb.com.br\\\/en\\\/terapia-de-luz-e-ritmos-biologicos\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/condor.fabbricaweb.com.br\\\/en\\\/terapia-de-luz-e-ritmos-biologicos\\\/\",\"url\":\"https:\\\/\\\/condor.fabbricaweb.com.br\\\/en\\\/terapia-de-luz-e-ritmos-biologicos\\\/\",\"name\":\"Light therapy and biological rhythms - 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